Item Type | Name |
Academic Article
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Use of granulocyte colony-stimulating factor before, during, and after fludarabine plus cytarabine induction therapy of newly diagnosed acute myelogenous leukemia or myelodysplastic syndromes: comparison with fludarabine plus cytarabine without granulocyte colony-stimulating factor.
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Academic Article
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Intravenous itraconazole for prophylaxis of systemic fungal infections in patients with acute myelogenous leukemia and high-risk myelodysplastic syndrome undergoing induction chemotherapy.
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Academic Article
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Liposomal amphotericin B versus the combination of fluconazole and itraconazole as prophylaxis for invasive fungal infections during induction chemotherapy for patients with acute myelogenous leukemia and myelodysplastic syndrome.
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Academic Article
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Amphotericin B lipid complex as prophylaxis of invasive fungal infections in patients with acute myelogenous leukemia and myelodysplastic syndrome undergoing induction chemotherapy.
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Academic Article
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Decitabine improves patient outcomes in myelodysplastic syndromes: results of a phase III randomized study.
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Academic Article
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RIL, a LIM gene on 5q31, is silenced by methylation in cancer and sensitizes cancer cells to apoptosis.
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Academic Article
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DNA methylation predicts survival and response to therapy in patients with myelodysplastic syndromes.
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Academic Article
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Treatment of myelodysplastic syndromes with AML-type chemotherapy.
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Academic Article
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Preliminary results of treatment with filgrastim for relapse of leukemia and myelodysplasia after allogeneic bone marrow transplantation.
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Academic Article
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Acute lymphoblastic leukemia following preleukemic syndromes in adults.
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Academic Article
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Association of comorbidities with overall survival in myelodysplastic syndrome: development of a prognostic model.
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Concept
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Myelodysplastic Syndromes
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Academic Article
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Implications of discrepancy in morphologic diagnosis of myelodysplastic syndrome between referral and tertiary care centers.
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Academic Article
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Impact of comorbidities by ACE-27 in the revised-IPSS for patients with myelodysplastic syndromes.
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Academic Article
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Differences in CD33 intensity between various myeloid neoplasms.
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Academic Article
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TET2 mutations predict response to hypomethylating agents in myelodysplastic syndrome patients.
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Academic Article
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Pneumonia during remission induction chemotherapy in patients with AML or MDS.
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Academic Article
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Engraftment of allogeneic hematopoietic progenitor cells with purine analog-containing chemotherapy: harnessing graft-versus-leukemia without myeloablative therapy.
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Academic Article
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Angiogenesis in acute and chronic leukemias and myelodysplastic syndromes.
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Academic Article
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Troxacitabine, a novel dioxolane nucleoside analog, has activity in patients with advanced leukemia.
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Academic Article
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Clinical significance of plasma endostatin in acute myeloid leukemia/myelodysplastic syndrome.
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Academic Article
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Farnesyltransferase inhibitors: novel compounds in development for the treatment of myeloid malignancies.
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Academic Article
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Ursodiol does not prevent hepatic venoocclusive disease associated with Mylotarg therapy.
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Academic Article
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A randomized trial of liposomal daunorubicin and cytarabine versus liposomal daunorubicin and topotecan with or without thalidomide as initial therapy for patients with poor prognosis acute myelogenous leukemia or myelodysplastic syndrome.
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Academic Article
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Contribution of beta-2 microglobulin levels to the prognostic stratification of survival in patients with myelodysplastic syndrome (MDS).
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Academic Article
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Antithymocyte globulin (ATG)-based therapy in patients with myelodysplastic syndromes.
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Academic Article
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Phase II study of R115777, a farnesyl transferase inhibitor, in myelodysplastic syndrome.
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Academic Article
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Adaptive randomized study of idarubicin and cytarabine alone or with interleukin-11 as induction therapy in patients aged 50 or above with acute myeloid leukemia or high-risk myelodysplastic syndromes.
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Academic Article
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Adult acute megakaryocytic leukemia: an analysis of 37 patients treated at M.D. Anderson Cancer Center.
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Academic Article
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Circulating levels and clinical significance of soluble CD40 in patients with hematologic malignancies.
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Academic Article
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Activity of 9-nitro-camptothecin, an oral topoisomerase I inhibitor, in myelodysplastic syndrome and chronic myelomonocytic leukemia.
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Academic Article
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Prospective feasibility analysis of reduced-intensity conditioning (RIC) regimens for hematopoietic stem cell transplantation (HSCT) in elderly patients with acute myeloid leukemia (AML) and high-risk myelodysplastic syndrome (MDS).
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Academic Article
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Soluble phosphorylated fms-like tyrosine kinase III. FLT3 protein in patients with acute myeloid leukemia (AML).
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Academic Article
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The role of decitabine in the treatment of myelodysplastic syndromes.
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Academic Article
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Red blood cell transfusions and iron overload in the treatment of patients with myelodysplastic syndromes.
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Academic Article
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Secondary myelodysplastic syndrome in a patient with Philadelphia-positive acute lymphoblastic leukemia after achieving a major molecular response with hyperCVAD plus imatinib mesylate.
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Academic Article
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Phase II study of rabbit anti-thymocyte globulin, cyclosporine and granulocyte colony-stimulating factor in patients with aplastic anemia and myelodysplastic syndrome.
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Academic Article
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Managing iron overload in patients with myelodysplastic syndromes with oral deferasirox therapy.
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Academic Article
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Cytogenetic abnormalities in essential thrombocythemia at presentation and transformation.
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Academic Article
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Superior outcome with hypomethylating therapy in patients with acute myeloid leukemia and high-risk myelodysplastic syndrome and chromosome 5 and 7 abnormalities.
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Academic Article
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Report of a phase 1/2 study of a combination of azacitidine and cytarabine in acute myelogenous leukemia and high-risk myelodysplastic syndromes.
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Academic Article
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Trisomy 11 in myelodysplastic syndromes defines a unique group of disease with aggressive clinicopathologic features.
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Academic Article
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Feasibility of therapy with hypomethylating agents in patients with renal insufficiency.
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Academic Article
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The search for better prognostic models in myelodysplastic syndromes.
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Academic Article
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Significance of thrombocytopenia in myelodysplastic syndromes: associations and prognostic implications.
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Academic Article
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A randomized study of 2 dose levels of intravenous clofarabine in the treatment of patients with higher-risk myelodysplastic syndrome.
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Academic Article
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Mechanisms of resistance to decitabine in the myelodysplastic syndrome.
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Academic Article
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A phase II study of lenalidomide alone in relapsed/refractory acute myeloid leukemia or high-risk myelodysplastic syndromes with chromosome 5 abnormalities.
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Academic Article
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Phase II trial of vorinostat with idarubicin and cytarabine for patients with newly diagnosed acute myelogenous leukemia or myelodysplastic syndrome.
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Academic Article
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Randomized, dose-escalation study of the p38a MAPK inhibitor SCIO-469 in patients with myelodysplastic syndrome.
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Academic Article
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Low frequency of H3.3 mutations and upregulated DAXX expression in MDS.
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Academic Article
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A phase II open-label study of the intravenous administration of homoharringtonine in the treatment of myelodysplastic syndrome.
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Academic Article
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Dynamic acquisition of FLT3 or RAS alterations drive a subset of patients with lower risk MDS to secondary AML.
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Academic Article
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Evolution of treatment for acute myelogenous leukemia and myelodysplastic syndrome at M.D. Anderson Cancer Center 1985-1991.
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Academic Article
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Effects of low doses of recombinant human granulocyte-macrophage colony stimulating factor (GM-CSF) in patients with myelodysplastic syndromes.
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Academic Article
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Detection of leukemic clone maturation in vivo by premature chromosome condensation.
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Academic Article
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Idarubicin cardiotoxicity: a retrospective study in acute myeloid leukemia and myelodysplasia.
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Academic Article
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Therapy-related leukemia and myelodysplastic syndrome in chronic lymphocytic leukemia.
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Academic Article
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Abnormalities in the long arm of chromosome 11 (11q) in patients with de novo and secondary acute myelogenous leukemias and myelodysplastic syndromes.
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Academic Article
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Myelodysplastic syndrome following successful therapy of acute promyelocytic leukemia.
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Academic Article
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Topotecan in the treatment of hematologic malignancies.
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Academic Article
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Results of topotecan single-agent therapy in patients with myelodysplastic syndromes and chronic myelomonocytic leukemia.
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Academic Article
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WT1 and GATA1 expression in myelodysplastic syndrome and acute leukemia.
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Academic Article
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Results of topotecan-based combination therapy in patients with myelodysplastic syndromes and chronic myelomonocytic leukemia.
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Academic Article
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Terminal deoxynucleotidyl transferase expression in acute myelogenous leukemia and myelodysplasia as determined by flow cytometry.
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Academic Article
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11q23 abnormalities in patients with acute myelogenous leukemia and myelodysplastic syndrome as detected by molecular and cytogenetic analyses.
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Academic Article
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Report of an international working group to standardize response criteria for myelodysplastic syndromes.
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Academic Article
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Loss of heterozygosity and heterogeneity of its appearance and persisting in the course of acute myeloid leukemia and myelodysplastic syndromes.
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Academic Article
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Mylotarg (gemtuzumab ozogamicin) therapy is associated with hepatic venoocclusive disease in patients who have not received stem cell transplantation.
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Academic Article
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A phase I study of idarubicin dose escalation with amisfostine and high-dose cytarabine in patients with relapsed acute myelogenous leukemia and myelodysplastic syndromes.
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Academic Article
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Better detection of FLT3 internal tandem duplication using peripheral blood plasma DNA.
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Academic Article
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Randomized phase I/II study of troxacitabine combined with cytarabine, idarubicin, or topotecan in patients with refractory myeloid leukemias.
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Academic Article
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SU5416, a small molecule tyrosine kinase receptor inhibitor, has biologic activity in patients with refractory acute myeloid leukemia or myelodysplastic syndromes.
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Academic Article
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Increased apoptosis in bone marrow B lymphocytes but not T lymphocytes in myelodysplastic syndrome.
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Academic Article
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Results of imatinib mesylate therapy in patients with refractory or recurrent acute myeloid leukemia, high-risk myelodysplastic syndrome, and myeloproliferative disorders.
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Academic Article
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Phase 2 clinical and pharmacologic study of clofarabine in patients with refractory or relapsed acute leukemia.
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Academic Article
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Farnesyltransferase inhibitor R115777 in myelodysplastic syndrome: clinical and biologic activities in the phase 1 setting.
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Academic Article
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Relative increase in leukemia-specific DNA in peripheral blood plasma from patients with acute myeloid leukemia and myelodysplasia.
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Academic Article
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A Phase I and pharmacokinetic study of VNP40101M, a novel sulfonylhydrazine alkylating agent, in patients with refractory leukemia.
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Academic Article
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Phase I study of BMS-214662, a farnesyl transferase inhibitor in patients with acute leukemias and high-risk myelodysplastic syndromes.
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Academic Article
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Azacitidine.
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Academic Article
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Drug insight: emerging new drugs in the treatment of myelodysplastic syndromes.
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Academic Article
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Clinical experience with decitabine in North American patients with myelodysplastic syndrome.
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Academic Article
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Results of intensive chemotherapy in 998 patients age 65 years or older with acute myeloid leukemia or high-risk myelodysplastic syndrome: predictive prognostic models for outcome.
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Academic Article
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Clinical application and proposal for modification of the International Working Group (IWG) response criteria in myelodysplasia.
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Academic Article
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Myelodysplastic syndromes and acute leukemia developing after imatinib mesylate therapy for chronic myeloid leukemia.
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Academic Article
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Results of a randomized study of 3 schedules of low-dose decitabine in higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia.
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Academic Article
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Levels of soluble HLA-I and beta2M in patients with acute myeloid leukemia and advanced myelodysplastic syndrome: association with clinical behavior and outcome of induction therapy.
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Academic Article
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Myelodysplastic syndromes: the complexity of stem-cell diseases.
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Academic Article
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The incidence and impact of thrombocytopenia in myelodysplastic syndromes.
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Academic Article
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Clofarabine: past, present, and future.
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Academic Article
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Phase 1 study of the histone deacetylase inhibitor vorinostat (suberoylanilide hydroxamic acid [SAHA]) in patients with advanced leukemias and myelodysplastic syndromes.
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Academic Article
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A prognostic score for patients with lower risk myelodysplastic syndrome.
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Academic Article
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Phase I study of alternate-week administration of tipifarnib in patients with myelodysplastic syndrome.
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Academic Article
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A pilot pharmacokinetic study of oral azacitidine.
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Academic Article
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Therapy-related acute myelogenous leukemia and myelodysplastic syndrome in patients with acute lymphoblastic leukemia treated with the hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone regimens.
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Academic Article
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Feasibility of allo-SCT after hypomethylating therapy with decitabine for myelodysplastic syndrome.
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Academic Article
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Accurate detection of uniparental disomy and microdeletions by SNP array analysis in myelodysplastic syndromes with normal cytogenetics.
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Academic Article
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Multicenter study of decitabine administered daily for 5 days every 4 weeks to adults with myelodysplastic syndromes: the alternative dosing for outpatient treatment (ADOPT) trial.
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Academic Article
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The heterogeneous prognosis of patients with myelodysplastic syndrome and chromosome 5 abnormalities: how does it relate to the original lenalidomide experience in MDS?
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Academic Article
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Acute pulmonary failure during remission induction chemotherapy in adults with acute myeloid leukemia or high-risk myelodysplastic syndrome.
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Academic Article
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Phase I clinical and pharmacokinetic study of oral sapacitabine in patients with acute leukemia and myelodysplastic syndrome.
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Academic Article
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Predictors and outcome of acute kidney injury in patients with acute myelogenous leukemia or high-risk myelodysplastic syndrome.
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Academic Article
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Subcutaneous or intravenous administration of romiplostim in thrombocytopenic patients with lower risk myelodysplastic syndromes.
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Academic Article
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A phase 1-2 study of a farnesyltransferase inhibitor, tipifarnib, combined with idarubicin and cytarabine for patients with newly diagnosed acute myeloid leukemia and high-risk myelodysplastic syndrome.
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Academic Article
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Pharmacokinetic evaluation of decitabine for the treatment of leukemia.
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Academic Article
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Failure of hypomethylating agent-based therapy in myelodysplastic syndromes.
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Academic Article
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Final results of the phase II study of rabbit anti-thymocyte globulin, ciclosporin, methylprednisone, and granulocyte colony-stimulating factor in patients with aplastic anaemia and myelodysplastic syndrome.
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Academic Article
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Twice-daily fludarabine and cytarabine combination with or without gentuzumab ozogamicin is effective in patients with relapsed/refractory acute myeloid leukemia, high-risk myelodysplastic syndrome, and blast- phase chronic myeloid leukemia.
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Academic Article
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Validation of a prognostic model and the impact of mutations in patients with lower-risk myelodysplastic syndromes.
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Academic Article
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Prognostic factors associated with disease progression and overall survival in patients with myelodysplastic syndromes treated with decitabine.
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Academic Article
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Allogeneic hematopoietic stem cell transplantation versus hypomethylating agents in patients with myelodysplastic syndrome: a retrospective case-control study.
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Academic Article
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Global H3K4me3 genome mapping reveals alterations of innate immunity signaling and overexpression of JMJD3 in human myelodysplastic syndrome CD34+ cells.
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Academic Article
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NRAS mutations with low allele burden have independent prognostic significance for patients with lower risk myelodysplastic syndromes.
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Academic Article
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Randomized open-label phase II study of decitabine in patients with low- or intermediate-risk myelodysplastic syndromes.
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Academic Article
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Acquisition of cytogenetic abnormalities in patients with IPSS defined lower-risk myelodysplastic syndrome is associated with poor prognosis and transformation to acute myelogenous leukemia.
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Academic Article
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Expression of PD-L1, PD-L2, PD-1 and CTLA4 in myelodysplastic syndromes is enhanced by treatment with hypomethylating agents.
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Academic Article
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Therapy-related leukemia and myelodysplastic syndrome.
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Academic Article
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Therapy-related leukemia and myelodysplastic syndrome: clinical, cytogenetic, and prognostic features.
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Academic Article
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Cytogenetic and clinical correlates in AML patients with abnormalities of chromosome 16.
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Academic Article
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Treatment of therapy-related leukemia and myelodysplastic syndrome.
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Academic Article
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Clinical and prognostic significance of trisomy 21 in adult patients with acute myelogenous leukemia and myelodysplastic syndromes.
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Academic Article
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Idarubicin plus continuous-infusion high-dose cytarabine as treatment for patients with acute myelogenous leukemia or myelodysplastic syndrome.
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Academic Article
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Lymphotoxin is an autocrine growth factor for Epstein-Barr virus-infected B cell lines.
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Academic Article
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Topotecan, a topoisomerase I inhibitor, is active in the treatment of myelodysplastic syndrome and chronic myelomonocytic leukemia.
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Academic Article
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Emergence of new clonal abnormalities following interferon-alpha induced complete cytogenetic response in patients with chronic myeloid leukemia: report of three cases.
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Academic Article
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Randomized phase II study of fludarabine + cytosine arabinoside + idarubicin +/- all-trans retinoic acid +/- granulocyte colony-stimulating factor in poor prognosis newly diagnosed acute myeloid leukemia and myelodysplastic syndrome.
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Academic Article
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High-dose chemotherapy in high-risk myelodysplastic syndrome: covariate-adjusted comparison of five regimens.
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Academic Article
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High expression of the receptor tyrosine kinase Tie-1 in acute myeloid leukemia and myelodysplastic syndrome.
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Academic Article
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Treatment of myelodysplastic syndrome: questions raised by the azacitidine experience.
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Academic Article
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Gemtuzumab ozogamicin with or without interleukin 11 in patients 65 years of age or older with untreated acute myeloid leukemia and high-risk myelodysplastic syndrome: comparison with idarubicin plus continuous-infusion, high-dose cytosine arabinoside.
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Academic Article
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Clinical relevance of vascular endothelial growth factor receptors 1 and 2 in acute myeloid leukaemia and myelodysplastic syndrome.
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Academic Article
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Myelodysplastic syndrome is not merely "preleukemia".
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Academic Article
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Future clinical implications for farnesyltransferase inhibitors in hematologic malignancies.
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Academic Article
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Clinical development of farnesyltransferase inhibitors in leukemias and myelodysplastic syndrome.
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Academic Article
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Gemtuzumab, fludarabine, cytarabine, and cyclosporine in patients with newly diagnosed acute myelogenous leukemia or high-risk myelodysplastic syndromes.
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Academic Article
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Outcome in patients with nonleukemic granulocytic sarcoma treated with chemotherapy with or without radiotherapy.
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Academic Article
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Soluble vascular endothelial growth factor receptor 1, and not receptor 2, is an independent prognostic factor in acute myeloid leukemia and myelodysplastic syndromes.
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Academic Article
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Phase I study of bortezomib in refractory or relapsed acute leukemias.
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Academic Article
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Novel therapies for myelodysplastic syndromes.
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Academic Article
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Phase 1 study of ABT-751, a novel microtubule inhibitor, in patients with refractory hematologic malignancies.
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Academic Article
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Phase 1/2 study of the combination of 5-aza-2'-deoxycytidine with valproic acid in patients with leukemia.
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Academic Article
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Results of a multicenter phase II trial for older patients with c-Kit-positive acute myeloid leukemia (AML) and high-risk myelodysplastic syndrome (HR-MDS) using low-dose Ara-C and Imatinib.
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Academic Article
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Clinical activity of tipifarnib in hematologic malignancies.
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Academic Article
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Survival advantage with decitabine versus intensive chemotherapy in patients with higher risk myelodysplastic syndrome: comparison with historical experience.
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Academic Article
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Effect of haematological improvement on survival in patients given targeted therapy as initial treatment of acute myeloid leukaemia or high-risk myelodysplastic syndrome.
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Academic Article
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Safety and clinical activity of the combination of 5-azacytidine, valproic acid, and all-trans retinoic acid in acute myeloid leukemia and myelodysplastic syndrome.
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Academic Article
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The prognosis for patients with chronic myeloid leukemia who have clonal cytogenetic abnormalities in philadelphia chromosome-negative cells.
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Academic Article
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Prognostic interaction between thrombocytosis and JAK2 V617F mutation in the WHO subcategories of myelodysplastic/myeloproliferative disease-unclassifiable and refractory anemia with ringed sideroblasts and marked thrombocytosis.
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Academic Article
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A randomized study of clofarabine versus clofarabine plus low-dose cytarabine as front-line therapy for patients aged 60 years and older with acute myeloid leukemia and high-risk myelodysplastic syndrome.
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Academic Article
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Characteristics of US patients with myelodysplastic syndromes: results of six cross-sectional physician surveys.
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Academic Article
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Proteasome enzymatic activities in plasma as risk stratification of patients with acute myeloid leukemia and advanced-stage myelodysplastic syndrome.
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Academic Article
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Targeting DNA methylation.
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Academic Article
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Adult acute erythroleukemia: an analysis of 91 patients treated at a single institution.
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Academic Article
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Efficacy and safety of intravenous voriconazole and intravenous itraconazole for antifungal prophylaxis in patients with acute myelogenous leukemia or high-risk myelodysplastic syndrome.
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Academic Article
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Safety and efficacy of romiplostim in patients with lower-risk myelodysplastic syndrome and thrombocytopenia.
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Academic Article
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Cause of death in patients with lower-risk myelodysplastic syndrome.
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Academic Article
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Oral clofarabine in the treatment of patients with higher-risk myelodysplastic syndrome.
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Academic Article
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Current and future management options for myelodysplastic syndromes.
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Academic Article
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Thrombocytopenia in patients with myelodysplastic syndromes.
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Academic Article
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Phase 2 study of romiplostim in patients with low- or intermediate-risk myelodysplastic syndrome receiving azacitidine therapy.
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Academic Article
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Significant association between polymorphism of the erythropoietin gene promoter and myelodysplastic syndrome.
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Academic Article
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Coalesced multicentric analysis of 2,351 patients with myelodysplastic syndromes indicates an underestimation of poor-risk cytogenetics of myelodysplastic syndromes in the international prognostic scoring system.
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Academic Article
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Clinical effect of point mutations in myelodysplastic syndromes.
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Academic Article
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Association of anemia and cognitive dysfunction in patients with acute myelogenous leukemia and myelodysplastic syndrome.
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Academic Article
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Phase II study of the histone deacetylase inhibitor panobinostat (LBH589) in patients with low or intermediate-1 risk myelodysplastic syndrome.
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Academic Article
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Predicting survival of patients with hypocellular myelodysplastic syndrome: development of a disease-specific prognostic score system.
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Academic Article
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Phase I-II study of bendamustine in patients with acute leukemia and high risk myelodysplastic syndrome.
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Academic Article
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Revised international prognostic scoring system for myelodysplastic syndromes.
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Academic Article
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CD30 expression in high-risk acute myeloid leukemia and myelodysplastic syndromes.
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Academic Article
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Prognostic impact of RAS mutations in patients with myelodysplastic syndrome.
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Academic Article
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Toll-like receptor alterations in myelodysplastic syndrome.
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Academic Article
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Retrospective analysis of prognostic factors associated with response and overall survival by baseline marrow blast percentage in patients with myelodysplastic syndromes treated with decitabine.
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Academic Article
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MYBL2 is a sub-haploinsufficient tumor suppressor gene in myeloid malignancy.
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Academic Article
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CD105 (endoglin) is highly overexpressed in a subset of cases of acute myeloid leukemias.
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Academic Article
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Decitabine can be safely reduced after achievement of best objective response in patients with myelodysplastic syndrome.
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Academic Article
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Clofarabine in the treatment of myelodysplastic syndromes.
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Academic Article
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The prognostic significance of bone marrow levels of neurofibromatosis-1 protein and ras oncogene mutations in patients with acute myeloid leukemia and myelodysplastic syndrome.
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Academic Article
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Beta-D-glucan as a diagnostic adjunct for invasive fungal infections: validation, cutoff development, and performance in patients with acute myelogenous leukemia and myelodysplastic syndrome.
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Academic Article
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Management of patients with systemic mastocytosis: review of M. D. Anderson Cancer Center experience.
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Academic Article
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Clofarabine in adult acute leukemias: clinical success and pharmacokinetics.
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Academic Article
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Azacitidine.
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Academic Article
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Prognostic significance of monocytosis in patients with myeloproliferative disorders.
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Academic Article
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Long-term follow-up results of the combination of topotecan and cytarabine and other intensive chemotherapy regimens in myelodysplastic syndrome.
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Academic Article
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A phase I study of intravenous LBH589, a novel cinnamic hydroxamic acid analogue histone deacetylase inhibitor, in patients with refractory hematologic malignancies.
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Academic Article
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Update of the decitabine experience in higher risk myelodysplastic syndrome and analysis of prognostic factors associated with outcome.
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Academic Article
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Recent experience with decitabine in MDS.
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Academic Article
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Evolution of decitabine development: accomplishments, ongoing investigations, and future strategies.
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Academic Article
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Proposal for a new risk model in myelodysplastic syndrome that accounts for events not considered in the original International Prognostic Scoring System.
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Academic Article
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Therapeutic advances in leukemia and myelodysplastic syndrome over the past 40 years.
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Academic Article
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Analysis of Aurora kinase A expression in CD34(+) blast cells isolated from patients with myelodysplastic syndromes and acute myeloid leukemia.
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Academic Article
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Decitabine in the treatment of myelodysplastic syndromes.
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Academic Article
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Levels of miR-29b do not predict for response in patients with acute myelogenous leukemia treated with the combination of 5-azacytidine, valproic acid, and ATRA.
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Academic Article
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Phase I study of oral azacitidine in myelodysplastic syndromes, chronic myelomonocytic leukemia, and acute myeloid leukemia.
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Academic Article
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A phase 1 dose-escalation study of ARRY-520, a kinesin spindle protein inhibitor, in patients with advanced myeloid leukemias.
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Academic Article
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FLT3 mutations in myelodysplastic syndrome and chronic myelomonocytic leukemia.
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Academic Article
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Results of a randomized, double-blind study of romiplostim versus placebo in patients with low/intermediate-1-risk myelodysplastic syndrome and thrombocytopenia.
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Academic Article
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Development and validation of a model to predict platelet response to romiplostim in patients with lower-risk myelodysplastic syndromes.
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Academic Article
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AML-associated cytogenetic abnormalities (inv (16), del (16), t(8;21)) in patients with myelodysplastic syndromes.
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Academic Article
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Causes of initial remission induction failure in patients with acute myeloid leukemia and myelodysplastic syndromes.
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Academic Article
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Topotecan and cytarabine is an active combination regimen in myelodysplastic syndromes and chronic myelomonocytic leukemia.
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Academic Article
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Highly reproducible detection and semi-quantification of telomerase activity.
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Academic Article
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Proliferation and apoptosis in acute and chronic leukemias and myelodysplastic syndrome.
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Academic Article
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Phase I and pharmacokinetic study of DX-8951f (exatecan mesylate), a hexacyclic camptothecin, on a daily-times-five schedule in patients with advanced leukemia.
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Academic Article
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Expression of constitutively active nuclear-kappa B RelA transcription factor in blasts of acute myeloid leukemia.
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Academic Article
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Having a higher blast percentage in circulation than bone marrow: clinical implications in myelodysplastic syndrome and acute lymphoid and myeloid leukemias.
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Academic Article
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A multicenter phase 2 study of the farnesyltransferase inhibitor tipifarnib in intermediate- to high-risk myelodysplastic syndrome.
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Academic Article
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Activity of decitabine in patients with myelodysplastic syndrome previously treated with azacitidine.
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Academic Article
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The prognostic significance of cytokine levels in newly diagnosed acute myeloid leukemia and high-risk myelodysplastic syndromes.
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Academic Article
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Outcome of patients with myelodysplastic syndrome after failure of decitabine therapy.
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Academic Article
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Ubiquitin-proteasome system profiling in acute leukemias and its clinical relevance.
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Academic Article
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Phase I study of sorafenib in patients with refractory or relapsed acute leukemias.
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Academic Article
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Integrating genetics and epigenetics in myelodysplastic syndromes: advances in pathogenesis and disease evolution.
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Academic Article
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Acute myeloid leukemia after myelodysplastic syndrome and failure of therapy with hypomethylating agents: an emerging entity with a poor prognosis.
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Academic Article
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The effect of decitabine dose modification and myelosuppression on response and survival in patients with myelodysplastic syndromes.
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Academic Article
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A prognostic model of therapy-related myelodysplastic syndrome for predicting survival and transformation to acute myeloid leukemia.
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Academic Article
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Characteristics and outcomes of patients with multiple myeloma who develop therapy-related myelodysplastic syndrome, chronic myelomonocytic leukemia, or acute myeloid leukemia.
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Academic Article
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Relationship of different platelet response criteria and patient outcomes in a romiplostim myelodysplastic syndromes trial.
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Academic Article
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Plasma circulating-microRNA profiles are useful for assessing prognosis in patients with cytogenetically normal myelodysplastic syndromes.
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Academic Article
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Second cancers in patients with chronic lymphocytic leukemia who received frontline fludarabine, cyclophosphamide and rituximab therapy: distribution and clinical outcomes.
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Academic Article
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Results of phase 2 randomized study of low-dose decitabine with or without valproic acid in patients with myelodysplastic syndrome and acute myelogenous leukemia.
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Academic Article
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Outcome of patients with low-risk and intermediate-1-risk myelodysplastic syndrome after hypomethylating agent failure: a report on behalf of the MDS Clinical Research Consortium.
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Academic Article
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A phase I study of oral ARRY-614, a p38 MAPK/Tie2 dual inhibitor, in patients with low or intermediate-1 risk myelodysplastic syndromes.
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Academic Article
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Phase I/II trial of the combination of midostaurin (PKC412) and 5-azacytidine for patients with acute myeloid leukemia and myelodysplastic syndrome.
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Academic Article
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Mutational profiling of therapy-related myelodysplastic syndromes and acute myeloid leukemia by next generation sequencing, a comparison with de novo diseases.
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Academic Article
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Validation of WHO classification-based Prognostic Scoring System (WPSS) for myelodysplastic syndromes and comparison with the revised International Prognostic Scoring System (IPSS-R). A study of the International Working Group for Prognosis in Myelodysplasia (IWG-PM).
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Academic Article
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Discontinuation of hypomethylating agent therapy in patients with myelodysplastic syndromes or acute myelogenous leukemia in complete remission or partial response: retrospective analysis of survival after long-term follow-up.
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Academic Article
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TP53 mutation characteristics in therapy-related myelodysplastic syndromes and acute myeloid leukemia is similar to de novo diseases.
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Academic Article
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Telomere dysfunction drives aberrant hematopoietic differentiation and myelodysplastic syndrome.
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Academic Article
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Comprehensive analysis of factors impacting risks and outcomes of therapy-related myeloid neoplasms following breast cancer treatment.
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Academic Article
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TP53 overexpression is an independent adverse prognostic factor in de novo myelodysplastic syndromes with fibrosis.
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Academic Article
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Jumping Translocations in Myeloid Malignancies Associated With Treatment Resistance and Poor Survival.
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Academic Article
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Safety and tolerability of guadecitabine (SGI-110) in patients with myelodysplastic syndrome and acute myeloid leukaemia: a multicentre, randomised, dose-escalation phase 1 study.
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Academic Article
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Detectable FLT3-ITD or RAS mutation at the time of transformation from MDS to AML predicts for very poor outcomes.
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Academic Article
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Rituximab plus hyper-CVAD alternating with MTX/Ara-C in patients with newly diagnosed mantle cell lymphoma: 15-year follow-up of a phase II study from the MD Anderson Cancer Center.
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Academic Article
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Sequential azacitidine and lenalidomide in patients with high-risk myelodysplastic syndromes and acute myeloid leukaemia: a single-arm, phase 1/2 study.
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Academic Article
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Treatment with PF-04449913, an oral smoothened antagonist, in patients with myeloid malignancies: a phase 1 safety and pharmacokinetics study.
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Academic Article
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Unraveling Myelodysplastic Syndromes: Current Knowledge and Future Directions.
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Academic Article
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Downregulation of Protection of Telomeres 1 expression in myelodysplastic syndromes with 7q deletion.
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Academic Article
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IDH1 and IDH2 mutations in myelodysplastic syndromes and role in disease progression.
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Academic Article
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Outcomes for patients with chronic lymphocytic leukemia and acute leukemia or myelodysplastic syndrome
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Academic Article
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Plasma circulating-microRNA profiles are useful for assessing prognosis in patients with cytogenetically normal myelodysplastic syndromes
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Academic Article
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Phase 2 study of low-dose clofarabine plus cytarabine for patients with higher risk myelodysplastic syndrome who have relapsed or are refractory to hypomethylating agents
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Academic Article
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TP53 mutation characteristics in therapy-related myelodysplastic syndromes and acute myeloid leukemia is similar to de novo diseases
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Academic Article
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Decitabine in myelodysplastic syndromes
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Academic Article
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A clinical trial for patients with acute myeloid leukemia or myelodysplastic syndromes not eligible for standard clinical trials
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Academic Article
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The efficacy of current prognostic models in predicting outcome of patients with myelodysplastic syndromes at the time of hypomethylating agent failure
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Academic Article
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CD33 is frequently expressed in cases of myelodysplastic syndrome and chronic myelomonocytic leukemia with elevated blast count
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Academic Article
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Phase 2, randomized, double-blind study of pracinostat in combination with azacitidine in patients with untreated, higher risk myelodysplastic syndromes
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Academic Article
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IDH1 and IDH2 mutations in myelodysplastic syndromes and role in disease progression
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Academic Article
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Hypomethylating strategies in leukemia and myelodysplastic syndromes
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Academic Article
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Comparison of risk stratification tools in predicting outcomes of patients with higher-risk myelodysplastic syndromes treated with azanucleosides
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Academic Article
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Sequential azacitidine and lenalidomide in patients with high-risk myelodysplastic syndromes and acute myeloid leukaemia
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Academic Article
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Interactions and relevance of blast percentage and treatment strategy among younger and older patients with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS)
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Academic Article
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A phase II study of decitabine and gemtuzumab ozogamicin in newly diagnosed and relapsed acute myeloid leukemia and high-risk myelodysplastic syndrome
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Academic Article
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Clinical implications of TP53 mutations in myelodysplastic syndromes treated with hypomethylating agents
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Academic Article
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Unraveling Myelodysplastic Syndromes
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Academic Article
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The incidence and impact of thrombocytopenia in myelodysplastic syndrome
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Academic Article
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Outcomes of patients with myelodysplastic syndromes who achieve stable disease after treatment with hypomethylating agents
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Academic Article
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A phase I study of oral ARRY-614, a p38 MAPK/Tie2 dual inhibitor, in patients with low or intermediate-1 risk myelodysplastic syndromes
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Academic Article
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Results of a randomized study of 3 schedules of low-dose decitabine in higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia [2]
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Academic Article
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The effect of decitabine dose modification and myelosuppression on response and survival in patients with myelodysplastic syndromes
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Academic Article
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Whole-arm translocation of der(5;17)(p10;q10) with concurrent TP53 mutations in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS)
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Academic Article
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Cytopenia levels for aiding establishment of the diagnosis of myelodysplastic syndromes
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Academic Article
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Rigosertib versus best supportive care for patients with high-risk myelodysplastic syndromes after failure of hypomethylating drugs (ONTIME)
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Academic Article
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Downregulation of Protection of Telomeres 1 expression in myelodysplastic syndromes with 7q deletion
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Academic Article
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A clinical trial for patients with acute myeloid leukemia or myelodysplastic syndromes not eligible for standard clinical trials.
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Academic Article
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A clinical trial for patients with acute myeloid leukemia or myelodysplastic syndromes not eligible for standard clinical trials.
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Academic Article
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Outcomes for patients with chronic lymphocytic leukemia and acute leukemia or myelodysplastic syndrome.
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Academic Article
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A phase II study of decitabine and gemtuzumab ozogamicin in newly diagnosed and relapsed acute myeloid leukemia and high-risk myelodysplastic syndrome.
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Academic Article
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Comparison of risk stratification tools in predicting outcomes of patients with higher-risk myelodysplastic syndromes treated with azanucleosides.
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Academic Article
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Rigosertib versus best supportive care for patients with high-risk myelodysplastic syndromes after failure of hypomethylating drugs (ONTIME): a randomised, controlled, phase 3 trial.
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Academic Article
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CD33 is frequently expressed in cases of myelodysplastic syndrome and chronic myelomonocytic leukemia with elevated blast count.
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Academic Article
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Interactions and relevance of blast percentage and treatment strategy among younger and older patients with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS).
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Academic Article
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Clinical implications of TP53 mutations in myelodysplastic syndromes treated with hypomethylating agents.
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Academic Article
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Outcomes of patients with myelodysplastic syndromes who achieve stable disease after treatment with hypomethylating agents.
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Academic Article
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Whole-arm translocation of der(5;17)(p10;q10) with concurrent TP53 mutations in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS): A unique molecular-cytogenetic subgroup.
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Academic Article
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Activity of the oral mitogen-activated protein kinase kinase inhibitor trametinib in RAS-mutant relapsed or refractory myeloid malignancies.
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Academic Article
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The efficacy of current prognostic models in predicting outcome of patients with myelodysplastic syndromes at the time of hypomethylating agent failure.
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Academic Article
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Time-dependent changes in mortality and transformation risk in MDS.
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Academic Article
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Impact of achievement of complete cytogenetic response on outcome in patients with myelodysplastic syndromes treated with hypomethylating agents.
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Academic Article
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Phase 2 study of low-dose clofarabine plus cytarabine for patients with higher-risk myelodysplastic syndrome who have relapsed or are refractory to hypomethylating agents.
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Academic Article
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Preleukaemic clonal haemopoiesis and risk of therapy-related myeloid neoplasms: a case-control study.
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Academic Article
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Cytopenia levels for aiding establishment of the diagnosis of myelodysplastic syndromes.
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Academic Article
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Outcome of Patients With Therapy-Related Acute Myeloid Leukemia With or Without a History of Myelodysplasia.
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Academic Article
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KIR gene haplotype: an independent predictor of clinical outcome in MDS patients.
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Academic Article
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Phase 2, randomized, double-blind study of pracinostat in combination with azacitidine in patients with untreated, higher-risk myelodysplastic syndromes.
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Academic Article
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An exploratory clinical trial of bortezomib in patients with lower risk myelodysplastic syndromes.
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Academic Article
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Vosaroxin in combination with decitabine in newly diagnosed older patients with acute myeloid leukemia or high-risk myelodysplastic syndrome.
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Academic Article
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The emerging role of immune checkpoint based approaches in AML and MDS.
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Academic Article
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A phase II trial of ruxolitinib in combination with azacytidine in myelodysplastic syndrome/myeloproliferative neoplasms.
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Academic Article
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Phase 1 dose escalation multicenter trial of pracinostat alone and in combination with azacitidine in patients with advanced hematologic malignancies.
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Academic Article
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Validation of a post-hypomethylating agent failure prognostic model in myelodysplastic syndromes patients treated in a randomized controlled phase III trial of rigosertib vs. best supportive care.
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Academic Article
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Randomized phase 2 study of low-dose decitabine vs low-dose azacitidine in lower-risk MDS and MDS/MPN.
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Academic Article
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Secondary Philadelphia chromosome acquired during therapy of acute leukemia and myelodysplastic syndrome.
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Academic Article
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Phase Ib Study of Glasdegib, a Hedgehog Pathway Inhibitor, in Combination with Standard Chemotherapy in Patients with AML or High-Risk MDS.
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Academic Article
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Impact of the number of mutations in survival and response outcomes to hypomethylating agents in patients with myelodysplastic syndromes or myelodysplastic/myeloproliferative neoplasms.
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Academic Article
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Final results of a phase 2, open-label study of indisulam, idarubicin, and cytarabine in patients with relapsed or refractory acute myeloid leukemia and high-risk myelodysplastic syndrome.
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Academic Article
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Clinical experience with the BCL2-inhibitor venetoclax in combination therapy for relapsed and refractory acute myeloid leukemia and related myeloid malignancies.
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Academic Article
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Hypomethylating agents in combination with immune checkpoint inhibitors in acute myeloid leukemia and myelodysplastic syndromes.
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Academic Article
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A Pilot Trial of Lirilumab With or Without Azacitidine for Patients With Myelodysplastic Syndrome.
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Academic Article
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A phase II study of omacetaxine mepesuccinate for patients with higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia after failure of hypomethylating agents.
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Academic Article
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Prognosis of patients with intermediate risk IPSS-R myelodysplastic syndrome indicates variable outcomes and need for models beyond IPSS-R.
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Academic Article
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Phase I study of ruxolitinib in previously treated patients with low or intermediate-1 risk myelodysplastic syndrome with evidence of NF-kB activation.
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Academic Article
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Safety and tolerability of lurbinectedin (PM01183) in patients with acute myeloid leukemia and myelodysplastic syndrome.
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Academic Article
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Differing clinical features between Japanese and Caucasian patients with myelodysplastic syndromes: Analysis from the International Working Group for Prognosis of MDS.
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Academic Article
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Hematologic malignancies and Li-Fraumeni syndrome.
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Academic Article
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Update on Immunotherapy in AML and MDS: Monoclonal Antibodies and Checkpoint Inhibitors Paving the Road for Clinical Practice.
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Academic Article
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Clonal hematopoiesis of indeterminate potential-associated mutations and risk of comorbidities in patients with myelodysplastic syndrome.
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Academic Article
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An oral fixed-dose combination of decitabine and cedazuridine in myelodysplastic syndromes: a multicentre, open-label, dose-escalation, phase 1 study.
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Academic Article
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NPM1 mutations define a specific subgroup of MDS and MDS/MPN patients with favorable outcomes with intensive chemotherapy.
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Academic Article
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Intensive chemotherapy is more effective than hypomethylating agents for the treatment of younger patients with myelodysplastic syndrome and elevated bone marrow blasts.
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Academic Article
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Guadecitabine (SGI-110) in patients with intermediate or high-risk myelodysplastic syndromes: phase 2 results from a multicentre, open-label, randomised, phase 1/2 trial.
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Academic Article
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Philadelphia chromosome-negative acute leukemia in patients with chronic myeloid leukemia.
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Academic Article
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Successful lenalidomide treatment in high risk myelodysplastic syndrome with germline DDX41 mutation.
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Academic Article
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Idarubicin, cytarabine, and nivolumab in patients with newly diagnosed acute myeloid leukaemia or high-risk myelodysplastic syndrome: a single-arm, phase 2 study.
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Academic Article
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CPX-351 (vyxeos) in AML.
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Academic Article
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Transcriptomic analysis implicates necroptosis in disease progression and prognosis in myelodysplastic syndromes.
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Academic Article
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t(11;16)(q23;p13)/KMT2A-CREBBP in hematologic malignancies: presumptive evidence of myelodysplasia or therapy-related neoplasm?
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Academic Article
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Genomic context and TP53 allele frequency define clinical outcomes in TP53-mutated myelodysplastic syndromes.
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Academic Article
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LILRB4 expression in chronic myelomonocytic leukemia and myelodysplastic syndrome based on response to hypomethylating agents.
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Academic Article
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Outcomes of acute myeloid leukemia with myelodysplasia related changes depend on diagnostic criteria and therapy.
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Academic Article
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Enasidenib in patients with mutant IDH2 myelodysplastic syndromes: a phase 1 subgroup analysis of the multicentre, AG221-C-001 trial.
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Academic Article
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Posttransplantation cyclophosphamide improves transplantation outcomes in patients with AML/MDS who are treated with checkpoint inhibitors.
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Academic Article
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Isavuconazole as Primary Antifungal Prophylaxis in Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome: An Open-label, Prospective, Phase 2 Study.
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Academic Article
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Results of a Phase 1/2a dose-escalation study of FF-10501-01, an IMPDH inhibitor, in patients with acute myeloid leukemia or myelodysplastic syndromes.
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Academic Article
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Oral cedazuridine/decitabine for MDS and CMML: a phase 2 pharmacokinetic/pharmacodynamic randomized crossover study.
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Academic Article
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Hypomethylating Agent Therapy in Myelodysplastic Syndromes With Chromosome 3 Abnormalities.
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Academic Article
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Treating Leukemia in the Time of COVID-19.
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Academic Article
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Natural history of newly diagnosed myelodysplastic syndrome with isolated inv(3)/t(3;3).
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Academic Article
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Romiplostim monotherapy in thrombocytopenic patients with myelodysplastic syndromes: long-term safety and efficacy.
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Academic Article
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Long-term follow-up for up to 5 years on the risk of leukaemic progression in thrombocytopenic patients with lower-risk myelodysplastic syndromes treated with romiplostim or placebo in a randomised double-blind trial.
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Academic Article
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Eprenetapopt (APR-246) and Azacitidine in TP53-Mutant Myelodysplastic Syndromes.
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Academic Article
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Distinct Immunophenotypes of T Cells in Bronchoalveolar Lavage Fluid From Leukemia Patients With Immune Checkpoint Inhibitors-Related Pulmonary Complications.
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Academic Article
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Evolutionary action score identifies a subset of TP53 mutated myelodysplastic syndrome with favorable prognosis.
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Academic Article
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Acute myeloid leukemia: Treatment and research outlook for 2021 and the MD Anderson approach.
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Academic Article
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Clinical, genomic, and transcriptomic differences between myelodysplastic syndrome/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis (MDS/MPN-RS-T) and myelodysplastic syndrome with ring sideroblasts (MDS-RS).
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Academic Article
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Activity of venetoclax-based therapy in chronic myelomonocytic leukemia.
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Academic Article
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A phase I/II study of the combination of quizartinib with azacitidine or low-dose cytarabine for the treatment of patients with acute myeloid leukemia and myelodysplastic syndrome.
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Academic Article
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Donor clonal hematopoiesis increases risk of acute graft versus host disease after matched sibling transplantation.
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Academic Article
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Only SF3B1 mutation involving K700E independently predicts overall survival in myelodysplastic syndromes.
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Academic Article
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Venetoclax plus intensive chemotherapy with cladribine, idarubicin, and cytarabine in patients with newly diagnosed acute myeloid leukaemia or high-risk myelodysplastic syndrome: a cohort from a single-centre, single-arm, phase 2 trial.
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Academic Article
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Phase II study of azacitidine with pembrolizumab in patients with intermediate-1 or higher-risk myelodysplastic syndrome.
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Academic Article
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Time to blur the blast boundaries.
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Academic Article
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Impact of frontline treatment approach on outcomes in patients with secondary AML with prior hypomethylating agent exposure.
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Academic Article
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The Evolution of Research and Therapy With Hypomethylating Agents in Acute Myeloid Leukemia and Myelodysplastic Syndrome: New Directions for Old Drugs.
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Academic Article
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Hypomethylating agents for the treatment of myelodysplastic syndromes and acute myeloid leukemia: Past discoveries and future directions.
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Academic Article
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Targeted therapy with the mutant IDH2 inhibitor enasidenib for high-risk IDH2-mutant myelodysplastic syndrome.
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Academic Article
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TP53-Mutated Myelodysplastic Syndrome and Acute Myeloid Leukemia: Biology, Current Therapy, and Future Directions.
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Academic Article
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Azacitidine plus venetoclax in patients with high-risk myelodysplastic syndromes or chronic myelomonocytic leukaemia: phase 1 results of a single-centre, dose-escalation, dose-expansion, phase 1-2 study.
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Academic Article
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Biologic features and clinical outcomes in newly diagnosed myelodysplastic syndrome with KMT2A rearrangements.
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Academic Article
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TP53-altered acute myeloid leukemia and myelodysplastic syndrome with excess blasts should be approached as a single entity.
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Academic Article
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High-resolution structural variant profiling of myelodysplastic syndromes by optical genome mapping uncovers cryptic aberrations of prognostic and therapeutic significance.
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Academic Article
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Prediction of survival with lower intensity therapy among older patients with acute myeloid leukemia.
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Academic Article
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Magrolimab in Combination With Azacitidine in Patients With Higher-Risk Myelodysplastic Syndromes: Final Results of a Phase Ib Study.
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Academic Article
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Characteristics of patients with myelodysplastic neoplasm and spliceosome mutations.
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Academic Article
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A phase 1/2 study of azacitidine, venetoclax and pevonedistat in newly diagnosed secondary AML and in MDS or CMML after failure of hypomethylating agents.
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Academic Article
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Performance of IPSS-M in patients with myelodysplastic syndrome after hypomethylating agent failure.
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Academic Article
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Early Mortality as a Quality Indicator in Frontline and Salvage Acute Myeloid Leukemia.
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Academic Article
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Phase 1/2 study of CPX-351 for patients with Int-2 or high risk International Prognostic Scoring System myelodysplastic syndromes and chronic myelomonocytic leukaemia after failure to hypomethylating agents.
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Academic Article
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Oral decitabine-cedazuridine versus intravenous decitabine for myelodysplastic syndromes and chronic myelomonocytic leukaemia (ASCERTAIN): a registrational, randomised, crossover, pharmacokinetics, phase 3 study.
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Academic Article
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Cytogenetic and Molecular Associations with Outcomes in Higher-Risk Myelodysplastic Syndromes Treated with Hypomethylating Agents plus Venetoclax.
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Academic Article
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Oral decitabine plus cedazuridine and venetoclax in patients with higher-risk myelodysplastic syndromes or chronic myelomonocytic leukaemia: a single-centre, phase 1/2 study.
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Academic Article
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Low-Dose Decitabine versus Low-Dose Azacitidine in Lower-Risk MDS.
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Academic Article
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Ivosidenib significantly reduces triazole levels in patients with acute myeloid leukemia and myelodysplastic syndrome.
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